Pittsford Panthers Football Fall 2025 Schedule
| Details | Date | Time | Opponent | Score | Location |
| September | |||||
| Box Score | Thu, 9/4/25 | 7:00 pm | Victor | W 17 - 27 | St. John Fisher College |
| Box Score | Fri, 9/12/25 | 6:00 pm | @ UPREP | L 20 - 39 | Marina Auto Stadium |
| Box Score | Fri, 9/19/25 | 7:00 pm | @ Webster Schroeder | W 17 - 7 | Webster Schroeder High School |
| Box Score | Fri, 9/26/25 | 7:00 pm | Fairport | L 34 - 21 | Pittsford Sutherland High School |
| October | |||||
| Box Score | Fri, 10/3/25 | 6:30 pm | @ Rush Henrietta | W 35 - 21 | Rush Henrietta High School |
| Box Score | Fri, 10/10/25 | 7:00 pm | Penfield | L 27 - 21 | Pittsford Sutherland High School |
| Game Info | Fri, 10/17/25 | 7:00 pm | @ McQuaid | McQuaid | |
| Game Info | Fri, 10/24/25 | 7:00 pm | Aquinas | Pittsford Sutherland High School | |
